Purpose: Screeninh test for Colorectal Cancer
- Easy one-step operation
- High sensitivity (50 ng/mL, 10ug/g stool)
- No dietary restrictions
- Results in 5 minutes
OC-Light method is used for the detection of hemoglobin in feces.
Patients with gastrointestinal disorders:
- ulcerative colitis
- colon cancer ( rectal bleeding, constipation, diarrhea, abnormal cramps, change in normal bowel movements, unexplained weight loss and fatigue ).
SPECIMEN COLLECTION & TEST PROCEDURE
- Remove the Green Cap of the Sampling Bottle
- Collect fecal samples by scraping the surface of the stool. Collect the amount necessary to cover the groove of the probe.
- Return the probe to the bottle. Tighten the cap securely and shake the bottle vigorously.
- Set up the sampling bottle, putting the green cap side down.
- Remove the white cap.
- Insert the strip into the sampling bottle from the dip side.
- Read the test result, presence of a blue line at the lower and upper center of the strip, at 5 minutes.
PRINCIPLE OF THE METHOD
OC-Light test detects HbAo in feces using an immunochromatographical method.
The HbAo in the sample binds to anti-human HbAo mouse anti-bodies and anti-human
HbAo rabbit anti-bodies that have been coated on blue polystyrene latex. The antigen-
antibody reactants are transferred on a membrane where they are captured by the
anti-human HbAo mouse anti-bodies that are immobilized on the membrane, forming
a blue line.
The anti-mouse IgG rabbit antibodies, which have been immobilized on the membrane,
form a blue line. This verifies that the reaction has occurred correctly and that the
anti-human HbAo mouse anti-bodies, which are coated on the blue polysterene latex,
Have been correctly transferred on the membrane.
BASED ON A STUDY “PERFORMANCE OF THE IMMUNOCHEMICAL FOBT IN PREDICTING LESIONS IN THE LOWER GIT.
(BY DR’S CHIANG, LEE, TU , CHIU, WU OF TAIWAN. )
The immunochemical fecal occult blood test was specific for predicting lesions in the lower gastrointestinal tract. However, the test did not adequately predict lesions in the upper gastrointestinal tract.
The fecal occult blood test is a convenient tool to screen for asymptomatic gastrointestinal bleeding.1 When the test result is positive, colonoscopy is the strategy of choice to investigate the source of bleeding.2,3 However, 13%–42% of patients can have a positive test result but a negative colonoscopy,4 and it has not yet been determined whether asymptomatic patients should then undergo evaluation of the upper gastrointestinal tract.
KIT COMPONENTS AND STORAGE OC-LIGHT
Stable until the expiration date printed on the label under a storage temperature of 1 – 30 deg.celsius.
Contains 2 ml of buffer solution and is stable until the expiration date printed on the label under a storage temp of 1 – 30 deg.celsius.
EXISTING CLIENTS OF OC LIGHT
- Colorectal clinic (The Medical City)
- Clinica Manila
- Antipolo Doctor’s
- Lourdes Hospital
- Pilar Medical Clinic
- UST Hospital
- Cardinal Hospital
- Dr. GoodHealth Clinic
- St. Lukes Hospital (Global City)